Baseline survey of psychosocial factors levels and their health effects in a cohort study of natural gas field workers / 中华劳动卫生职业病杂志

Objective: To investigate the level of psychosocial factors in workplace and their health effects among workers in a natural gas field. Methods: A prospective and open cohort of natural gas field workers was established to study the level of workplace psychosocial factors and their health effects, with a follow-up every 5 years. In October 2018, a cluster sampling method was used to conduct a baseline survey of 1737 workers in a natural gas field, including a questionnaire survey on demographic characteristics, workplace psychosocial factors and mental health outcomes, physiological indicators such as height and weight, and biochemical indicators such as blood routine, urine routine, liver function and kidney function. The baseline data of the workers were statistically described and analyzed. The psychosocial factors and mental health outcomes were divided into high and low groups according to the mean score, and the physiological and biochemical indicators were divided into normal and abnormal groups according to the reference range of normal values. Results: The age of 1737 natural gas field workers was (41.8±8.0) years old, and the length of service was (21.0±9.7) years. There were 1470 male workers (84.6%). There were 773 (44.5%) high school (technical secondary school) and 827 (47.6%) college (junior college) graduates, 1490 (85.8%) married (including remarriage after divorce), 641 (36.9%) smokers and 835 (48.1%) drinkers. Among the psychosocial factors, the detection rates of high levels of resilience, self-efficacy, colleague support and positive emotion were all higher than 50%. Among the mental health outcomes evaluation indexes, the detection rates of high levels of sleep disorder, job satisfaction and daily stress were 41.82% (716/1712), 57.25% (960/1677) and 45.87% (794/1731), respectively. The detection rate of depressive symptoms was 22.77% (383/1682). The abnormal rates of body mass index (BMI), triglyceride and low density lipoprotein were 46.74% (810/1733), 36.50% (634/1737) and 27.98% (486/1737), respectively. The abnormal rates of systolic blood pressure, diastolic blood pressure, uric acid, total cholesterol and blood glucose were 21.64% (375/1733), 21.41% (371/1733), 20.67% (359/1737), 20.55% (357/1737) and 19.17% (333/1737), respectively. The prevalence rates of hypertension and diabetes were 11.23% (195/1737) and 3.45% (60/1737), respectively. Conclusion: The detection rates of high level psychosocial factors in natural gas field workers are high, and their effects on physical and mental health remain to be verified. The establishment of a cohort study of the levels and health effects of psychosocial factors provides an important resource for confirming the causal relationship between workplace psychosocial factors and health.

Preparation of Silver Nanowires Flexible Electrode for Electrochemical Detection of Trace Copper in Water / 分析化学

A silver nanowires(AgNWs) flexible electrode was prepared using polydimethylsiloxane (PDMS) as the substrate and AgNWs as the conductive layer. It is easier to change the shapes and sizes of the flexible electrode due to its excellent stretchability and foldability. A square wave stripping voltammetry (SWSV) method for the detection of trace copper in water was established using the electrode as the working electrode.The characterization of AgNWs flexible electrode showed that the spread of AgNWs was uniform and the average resistance was 1.03 Ω. The data of electrochemical analysis showed that the properties of the electrode were superior to commercialized gold electrode and silver electrode. The effects of Bi3+concentration, supporting electrolyte,pH value, enrichment potential and enrichment time were determined and optimized. We achieved the sharpest and highest peak of the SWSV curves for the detection of Cu2+in the range of-0.3-0.3 V,which means the most sensitive detection, under the following conditions such as 0.5 mg/L Bi3+,0.1 mol/L support electrolyte tartaric acid-sodium tartrate solution (pH, 4.8), 0.6 V of enrichment potential, and 600 s of enrichment time. Under such conditions, the linear detection range of Cu2+concentration was from 0.001 mg/L to 0.100 mg/L and the detection limit was 9.27×10-5mg/L. The advantages of this detection method are fast speed,high sensitivity and wide detection range. Therefore,it can not only meet the requirements for the copper ion detection but also provide a new method or experimental basis for the detection of other metal ions in water. In addition, the AgNWs flexible electrode has great potential in detections under special circumstances or instantaneous detections due to its wonderful flexibility and biocompatibility.

Effects of Sel1L on properties of bone marrow derived dendritic cells / 中国免疫学杂志

Objective:To explore the effects of suppress or enhancer of lin-12-like(Sel1L) on differentiation and function of bone marrow-derived dendritic cells.Methods:To generate conditional knockout mice by the Cre-Loxp recombination system.ELISA and Real-time fluorescence quantitative PCR(RT-PCR) was used for analyzing the protein levels and mRNA levels of IL-6/IL-12 in BMDCs.The protein levels of Sel1L in BMDCs were detected by Western bolt.The expression of CFSE,CD80,CD86,MHC-Ⅰ,MHC-Ⅱon BMDCs and the capability in priming OVA specific CD4+T cells proliferation were analyzed by the flow cytometry.Results:The deficiency of Sel1L decreases the proliferation of DCs during its differentiation,up-regulates the secretion of IL-6,IL-12 and the expression of MHC-Ⅰ.Notably,Sel1L-null DCs was failed to up-regulate MHC-Ⅱexpression and dramatically impaired their ability to prime OVA323-339specific CD4+T cell.Conclusion:The deletion of Sel1L can reduce the proliferation of BMDCs and down-regulate its ability in priming the proliferation of OVA specific CD4+T cells.

The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population / 生物医学与环境科学（英文）

Noise-induced hearing loss (NIHL) is a complex disease caused by interactions between environmental and genetic factors. This study investigated whether genetic variability in protocadherin related 15 (PCDH15) underlies an increased susceptibility to the development of NIHL in a Chinese population. The results showed that compared with the TT genotype of rs11004085, CT/CC genotypes were associated with an increased risk of NIHL [adjusted odds ratio (OR) = 2.64; 95% confidence interval (CI): 1.14-6.11, P = 0.024]. Additionally, significant interactions between the rs11004085 and rs978842 genetic variations and noise exposure were observed in the high-level exposure groups (P < 0.05). Furthermore, the risk haplotype TAGCC was observed when combined with higher levels of noise exposure (P < 0.05). Thus, our study confirms that genetic variations in PCDH15 modify the susceptibility to NIHL development in humans.

Expressions of chemokine CXCL12 and its receptor CXCR4 in human sperm / 中华男科学杂志

<p><b>OBJECTIVE</b>To explore the expression patterns of the chemokine CXCL12 and its receptor CXCR4 in human sperm.</p><p><b>METHODS</b>We collected semen samples from 10 fertile men, performed density gradient centrifugation, and then determined the expressions of both CXCL12 and CXCR4 in the sperm by RT-PCR and immunofluorescence staining.</p><p><b>RESULTS</b>RT-PCR revealed the mRNA expressions of CXCL12 (0.641 +/- 0.180) and CXCR4 (0.464 +/- 0.100) in the sperm. However, only CXCR4 rather than CXCL12 was expressed at the protein level, and the positive staining for CXCR4 was observed mainly in the posterior part of the acrosome.</p><p><b>CONCLUSION</b>CXCL12 and CXCR4 are involved as important molecules in regulating the function of human sperm.</p>

Co-effect of Demand-control-support model and effort-reward imbalance model on depression risk estimation in humans: findings from Henan Province of China / 生物医学与环境科学（英文）

<p><b>OBJECTIVE</b>To investigate the co-effect of Demand-control-support (DCS) model and Effort-reward Imbalance (ERI) model on the risk estimation of depression in humans in comparison with the effects when they are used respectively.</p><p><b>METHODS</b>A total of 3 632 males and 1 706 females from 13 factories and companies in Henan province were recruited in this cross-sectional study. Perceived job stress was evaluated with the Job Content Questionnaire and Effort-Reward Imbalance Questionnaire (Chinese version). Depressive symptoms were assessed by using the Center for Epidemiological Studies Depression Scale (CES-D).</p><p><b>RESULTS</b>DC (demands/job control ratio) and ERI were shown to be independently associated with depressive symptoms. The outcome of low social support and overcommitment were similar. High DC and low social support (SS), high ERI and high overcommitment, and high DC and high ERI posed greater risks of depressive symptoms than each of them did alone. ERI model and SS model seem to be effective in estimating the risk of depressive symptoms if they are used respectively.</p><p><b>CONCLUSION</b>The DC had better performance when it was used in combination with low SS. The effect on physical demands was better than on psychological demands. The combination of DCS and ERI models could improve the risk estimate of depressive symptoms in humans.</p>

The epidemiological characteristics and correlated factors of daily hassles for thermal power plant workers / 中华预防医学杂志

<p><b>OBJECTIVE</b>This study aimed to investigate the epidemiological characteristics and correlated factors of daily hassles among thermal power plant workers.</p><p><b>METHODS</b>A mass screening of daily hassles and correlated factors was conducted on 498 workers from a thermal power plant in Zhengzhou in July, 2008. The questionnaires included Daily Hassles Questionnaires, Work Roles Questionnaires, Job Content Questionnaires (Chinese version), Effort-Reward Imbalance (Chinese version), Work Locus of Control Scale and Type A Behavior Scale, with content covering demographic characters and occupational stress correlated factors among subjects. The daily hassles was divided into lower level and higher level according to scores, and the epidemiological characteristics and correlated factors of daily hassles were analyzed.</p><p><b>RESULTS</b>A total of 446 qualified questionnaires were obtained, effective response rate was 89.6% (446/498). For respondents, the age was (36.96 ± 6.49) years old, working length of the current job was (12.05 ± 7.54) years, the daily hassles scores was (9.01 ± 2.50), and the prevalence rate of the higher level of daily hassles was 34.1% (152/446). The multiple non-conditional logistic regression analysis showed 5-14 years' working length of current job (OR = 0.451, 95%CI: 0.225 - 0.904), average income > 3000 yuan(OR = 0.372, 95%CI: 0.202 - 0.684), reward (OR = 0.557, 95%CI: 0.325 - 0.954) and coping strategy (OR = 0.552, 95%CI: 0.330 - 0.925) were negatively correlated with daily hassles, and shift-work (OR = 1.887, 95%CI: 1.108 - 3.215), effort (OR = 2.053, 95%CI: 1.198 - 3.519), psychological demand (OR = 1.797, 95%CI: 1.049 - 3.078), negative affectivity (OR = 3.421, 95%CI: 2.065 - 5.668) were positively correlated with daily hassles.</p><p><b>CONCLUSION</b>The prevalence rate of the higher level of daily hassles was considerable high for thermal power plant workers. Its negative correlated factors included 5 - 14 years' working length of the current job, average income > 3000 yuan, reward and coping strategy and its positive corelated factors included shift-work, effort, psychological demand and negative affectivity.</p>

Association between occupational stress and musculoskeletal disorders in lower extremity / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the relationship between occupational stress and musculoskeletal disorders in lower extremity.</p><p><b>METHODS</b>The cross-sectional study was used to investigate 5338 workers in 13 factories and companies for prevalence of musculoskeletal disorders in lower extremity, working postures and occupational stress were investigated with questionnaires for past year. Perceived occupational stress was evaluated by the Chinese version of the Job Content Questionnaire (JCQ) and Effort-Reward Imbalance (ERI) Model Questionnaire. Logistic regression analyses were conducted to estimate the associations between occupational stress and prevalence of musculoskeletal disorders in lower extremity.</p><p><b>RESULTS</b>In the main dimensions of job strain and ERI model, physical demands and effort were risk factors of hip disorders, but job control was a protective factor of hip disorders. When job strain and ERI model scales were analyzed simultaneously, only physical demands were risk factor of hip disorders. When job strain and the effort-reward imbalance were computed by creating four independent categories, job strain was a risk factor of hip disorders, ERI was a risk factor of hip and knee disorders. The risk of imbalance between job strain and effort-reward the protective effect of job control increased with the disorder regions. According to continuous variable analysis, job strain by calculated with physical demands was risk factor of hip disorders, continuous ERI variable was risk factor of hip and knee disorders.</p><p><b>CONCLUSION</b>Occupational stress is associated significantly with musculoskeletal disorders in lower extremity. The control of occupational stress and increase of job control should be considered for preventing the musculoskeletal disorders in lower extremity.</p>

Gender difference of relationship between occupational stress and depressive symptoms / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore gender difference of relationship between occupational stress and depressive symptoms.</p><p><b>METHODS</b>The cross-sectional study was used to investigate 5338 workers in 13 factories and companies, the depressive symptoms were assessed with Epidemiologic Studies Depression Scale (CES-D) and the perceived occupational stress was evaluated by the Chinese version of the Job Content Questionnaire (JCQ) and Effort-Reward Imbalance (ERI) Model Questionnaire. Logistic regression analyses were conducted to estimate the associations between occupational stress and prevalence of depressive symptoms.</p><p><b>RESULTS</b>Prevalence of depressive symptoms was 31.8% for all subjects, 33.8% for males and 27.7% for females, gender difference of prevalence was significant (P < 0.01). Psychological demands, physical demands, job control, effort, overcommitment and negative affectivity scores for males were significantly higher than those for females(P < 0.01 or 0.05), social support, reward and job satisfaction scores for males were significantly lower than those for females (P < 0.01). Psychological demands, physical demands, job control, effort, overcommitment and negative affectivity scores for workers with depressive symptoms were significantly higher than those for workers without depressive symptoms (P < 0.01) but job control, social support, reward, job satisfaction and positive affectivity scores for workers with depressive symptoms were significantly lower than those for without depressive symptoms (P < 0.01). Psychological demands, physical demands, job control, effort, overcommitment and negative affectivity scores for male workers with depressive symptoms were significantly higher than those for female counterparts (P < 0.01), but social support, reward, job satisfaction scores for male workers with depressive symptoms were significantly lower than hose for female workers with depressive symptoms (P < 0.01). Ratio of male workers and male workers with depressive symptoms with job strain and ERI > 1, high demands and low control, and high effort and low reward were higher than female counterparts (P < 0.01). The risk of depressive symptoms for female with high demands and low control was about two times as high as that for female workers with low demands and high control for psychological demands and physical demands (OR = 2.0), risk for females was slightly higher than that for males (OR = 2.04 and 2.17, respectively). The risk of depressive symptoms for workers with high efforts and low rewards was about two times as high as that for workers with low efforts and high rewards (OR = 1.70). No interactive effect between gender and job strain and ERI on depressive symptoms were found.</p><p><b>CONCLUSION</b>The gender difference of relationship between depressive symptom prevalence and job strain may due to the difference of psychosocial factors between females and males. There may be no interactive effect between psychosocial factors and gender on depressive symptoms.</p>

Relationship between job satisfaction and occupational stress in the workers of a thermal power plant / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the relationship between job satisfaction and occupational stress in the workers of a thermal power plant.</p><p><b>METHODS</b>The cluster sampling method was used to investigate 875 workers in a thermal power plant. The job satisfaction, occupational stressors, strains, personalities, meeting strategy and social support were measured using occupational stress instruments, job content questionnaire and effort-reward imbalance questionnaire.</p><p><b>RESULTS</b>There were no significant differences of job satisfaction scores between different groups according to sex, educational level, marriage status, smoking and drinking (P > 0.05). But there were significant differences of job satisfaction scores between different age groups or between different service length groups (P < 0.01). The correlation analysis revealed that job satisfaction scores were related positively to responsibility for persons and things, promotion opportunity, job control, job stabilization, rewards, mental health, positive affectivity, self-esteem, superior support and coworker support scores (P < 0.05 or P < 0.01), negatively to role ambiguity and conflict, job future ambiguity, job demands, negative affectivity, depressive symptoms, patience, and mental locus of work control(P < 0.05 or P < 0.01). The results of variance analysis indicated that the job relationship, responsibility for persons and things, promotion opportunity, job control, job stabilization, reward, mental health, positive affectivity, self-esteem and buffer scores of the workers with high job satisfaction scores were significantly higher than those of workers with moderate and lower job satisfaction scores (P < 0.01), but the role ambiguity and conflict, job future ambiguity, job demands, and depressive symptoms scores and mental locus of work control of the workers with high job satisfaction scores were significantly lower than those of workers with moderate and lower job satisfaction scores (P < 0.05 or P < 0.01). The results of multivariate logistic regression analysis showed that the risk of job dissatisfaction for workers with low reward was about four times as high as that for workers with high reward (OR = 3.773), the risks of job dissatisfaction for workers with low social support and mental locus of external work control were about two times as high as that for workers with high social support or mental locus of internal work control (OR = 2.419 and 2.219, respectively). The daily life stress, low control strategy, low support strategy, low job control and negative affectivity were risk factors of job dissatisfaction (OR = 1.125 approximately 1.790), but the self-esteem and positive affectivity could reduce the risk of job dissatisfaction.</p><p><b>CONCLUSION</b>Increasing the decision level, social support, meeting strategy and reward or decreasing the role conflict and ambiguity, demands and negative affectivity could improve worker's job satisfaction level.</p>

Effects of occupational stress on serum tumor necrosis factor-α and interleukins / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the effect of occupational stress on serum tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-2 and IL-4.</p><p><b>METHODS</b>A cross-sectional epidemiological study was conducted in 200 workers from the refrigerator assembly line in Henan province in China. Psychosocial work conditions were measured by using the job demand-control model, the effort-reward imbalance model questionnaires and occupational stress measurement scale. Serum TNF-α, IL-1β, IL-2, and IL-4 concentrations were measured by radioimmunoassay or immunoradiometric assay method respectively.</p><p><b>RESULTS</b>Serum TNF-α concentration was statistically significantly different between workers with higher affective balance level and control groups [(1.947 ± 0.173) and (2.029 ± 0.240) fmol/ml] (P < 0.05). Serum IL-1β concentration was statistically significantly different between workers with higher effort level and control groups [(0.133 ± 0.034) and (0.118 ± 0.031) ng/ml] (P < 0.05). Serum IL-2 concentration was statistically significantly different between workers with higher role ambiguity level [(1.658 ± 0.376) and (1.491 ± 0.033) ng/ml] and control groups (P < 0.05), as well as between workers with higher role conflict level and control groups [(1.774 ± 0.311) and (1.589 ± 0.380) ng/ml] (P < 0.05), between workers with higher daily life stress level and control groups [(1.759 ± 0.361) and (1.606 ± 0.381) ng/ml] (P < 0.05). Serum IL-4 concentration was statistically significantly different between workers with higher reward level and control groups [(1.449 ± 0.025) and (1.466 ± 0.041) pg/ml] (P < 0.05). Stepwise regression analysis indicated that affective balance was the predictor of serum TNF-α (R(2) = 0.029). Effort and mental health were the predictors of serum IL-1β (R(2) was 0.029 and 0.055, respectively). Role conflict, daily life stress and role ambiguity were the predictors of serum IL-2 (R(2) was 0.040, 0.078 and 0.104, respectively). Reward was the predictor of serum IL-4 (R(2) = 0.030).</p><p><b>CONCLUSION</b>Unhealthy psychological stress factor might be induce a marked increase in the concentrations of serum TNF-α, IL-1β, IL-2, as well as IL-4.</p>

Effect of occupational stress on hypertension / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the effect of occupational stress on hypertension.</p><p><b>METHODS</b>498 workers whose accumulative length of service was more than two years were investigated with questionnaire by method of cluster sampling from a thermal power plant in Henan province in China; 446 respondents returned qualified questionnaire including 281 male and 165 female Han People. After the patients with secondary hypertension, diabetes patients, and patients with liver or kidney disease were excluded, 84 workers (58 males and 26 females) were diagnosed as hypertension. The occupational stressors, personalities, buffering factors and occupational strain were measured by using the Job Demand-control Model, the Effort-reward Imbalance Model questionnaires and Occupational Stress Measurement Scale. Main risk factors for the development of hypertension such as heredity, body mass index, high salt diet, alcohol use, smoking habit and lack of physical activity were investigated. 498 whole blood samples were collected from workers in field epidemiologic survey. All of the samples were detected TG, CHO and FPG by common biochemistry methods. Multivariate logistic regression analysis were used to determine the relationship between occupational stressors and prevalence rate of hypertension. The difference of morbidity of hypertension between different stress level subjects was analyzed by chi2 test.</p><p><b>RESULTS</b>(1) Logistic regression analysis of the hypertension by all occupational stressors and risk factors of hypertension indicated that not only some common factors such as parents' hypertensive history, BMI, alcohol use and TG, but also responsibility for person, work locus of control and social support were significantly correlated with elevated risks of hypertension. (2) Logistic regression analysis of the hypertension by main dimensions of effort-reward imbalance model and risk factors of hypertension indicated that parents' hypertensive history, BMI, alcohol use, TG, and effort were significantly correlated with elevated risks of hypertension. Logistic regression analysis indicated the risk of hypertension had an effect on the FRI and effort (OR was 1.71 and 2.43 respectively). (3) For the job strain model, results indicated that parents' hypertensive history, UMI, alcohol use, TG, work locus of control and social support were significantly correlated with elevated risks of hypertension. But the main dimensions of job strain model (job demands and decision latitude) didn't enter regression equation. (4) The difference of prevalence of hypertension between high- and low stress level groups in male was statistically significant (OR = 3.13, P < 0.01), but the case was not the same in female (P > 0.05).</p><p><b>CONCLUSIONS</b>Occupational stress might be risk factor of hypertension; The predictive power of effort-reward imbalance model for the development of hypertension would be larger than that of job strain model.</p>

Effect of occupational stress on ambulatory blood pressure / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the effect of occupational stress on ambulatory blood pressure.</p><p><b>METHODS</b>30 male healthy workers from the refrigerator assembly line in Henan province in China were investigated. Psychosocial work conditions were measured by using the Job Demand-control Model, the Effort-reward Imbalance Model questionnaires and Occupational Stress Measurement Scale. Ambulatory blood pressure(ABP) was measured by using mobile ABP monitor. The t test was utilized to analyze the difference of parameters of ABP monitoring between different groups of occupational stress and other variables scores. The stepwise regression analysis was used to analyse the effect of occupational stress factors on parameters of ABP.</p><p><b>RESULTS</b>(1) As to stressors, systolic blood pressure variability (SBPV), mean arterial blood pressure variability (MABPV) and heart rate at 30 minute after work in workers with high role conflict score were significantly higher than those in workers with low score (P < 0.05). Workers with high skill utilization score had significantly lower mean systolic blood pressure (SBP) at 30 minute after work than workers with low score (P < 0.05). Diastolic blood pressure variability (DBPV) and heart rate variability (HRV) in workers with high decision latitude score were significantly higher than those in workers with low score (P < 0.05). Workers with high job psychological demands score had significantly higher SBPV, DBPV and MABPV than workers with low score (P < 0.05). Heart rate-pressure product(RPP) and SBPV in workers with high effort score were significantly higher than those in workers with low score (P < 0.05). Workers with low rewards score had higher mean heart rate and heart rate at 30 minute after work than workers with high score (P < 0.05). (2) For personalities, workers with high work locus of control score had significantly higher mean diastolic blood pressure (DBP) and mean arterial blood pressure (MABP) than workers with low score (P < 0.05). Workers with high patience score had significantly lower mean SBP at 30 minute after work than workers with low score (P < 0.05). Heart rate at 30 minute after work in workers with high organization commitment score was significantly lower than that in workers with low score (P < 0.05). (3) Concerning buffer factors, HRV in workers with high control strategies score were significantly lower than that in workers with low score (P < 0.05). Workers with low supervisor support score had higher RPP and MABPV than workers with high score (P < 0.05). (4) In the multiple stepwise regression, daily life stress affected SBPV (R2 = 0.12) and MABPV (R2 = 0.05), depression was related to DBPV at 30 minute after work (R2 = 0.15) and SBPV (R = 0.03), mental health was predictor of MABPV (R2 = 0.07) and negative affection was predictor of heart rate at 30 minute after work (R2 = 0.24).</p><p><b>CONCLUSIONS</b>Occupational stressors, personality and social support have effect on parameters of ABP. Parameters of ABP monitoring could be used to evaluate occupational stress in the field research.</p>

Job stress, gene polymorphism of beta2-AR, and prevalence of hypertension / 生物医学与环境科学（英文）

<p><b>OBJECTIVE</b>To study the interactive effect of job stress and genetic susceptibility (or gene polymorphism) on hypertension.</p><p><b>METHODS</b>A cross-sectional epidemiological study was conducted in 452 workers from a thermal power plant in China. Extrinsic effort, occupational reward, and over-commitment were measured. Hypertensive patients were defined by three phases of screening, reexamination, and final diagnosis. beta2-AR genotypes and allele frequencies at amino acid positions 16 (beta2-AR-16: Arg-->Gly) and 27 (beta2-AR-27: Gln-->Glu) were identified by PCR-RFLP.</p><p><b>RESULTS</b>Job stress was related with the prevalence of hypertension in males (P < 0.05), whereas no significant relationship was found in females (P > 0.05). Differences in genotypes and allele frequencies of the beta2-AR-16 were statistically significant between the hypertension and control groups (P < 0.05), whereas those of beta2-AR-27 were not (P > 0.05). The prevalence of hypertension was higher in individuals carrying Gly16 allele than in those carrying Arg16 allele of the high job stress group (P < 0.01 or 0.05).</p><p><b>CONCLUSION</b>High job stress and polymorphism of beta2-AR-16 have an interactive effect on the prevalence of hypertension in male workers.</p>

Influence of affectivity trait on relationships between occupational stress and subjective physical health and job satisfaction / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the influence of affectivity trait on relationships between occupational stress and subjective physical health and job satisfaction.</p><p><b>METHODS</b>Self-reports for psychosocial work conditions and health and well-being in a sample of 878 workers from a thermal power plant in China were conducted using the job demand-control model, the effort-reward imbalance model, job satisfaction, depression symptom, and physical health complaints questionnaires. Logistic regression analysis was used by controlling for age, sex, and educational level.</p><p><b>RESULTS</b>Negative and positive affectivity were correlated with occupational stressors or strains (P<0.01). In the most equation of job dissatisfaction, psychosomatic complaints and depressive symptoms as dependent variables respectively, odds ratios decreased greatly when negative affectivity or positive affectivity was controlled; Odds ratios decreased greater when negative affectivity and positive affectivity were controlled simultaneously. Furthermore in some equation no variable entered.</p><p><b>CONCLUSION</b>Affectivity trait has effect on relationships between occupational stress and subjective physical health and job satisfaction. According to the outcome category of study, the possible confounding role of affectivity should be controlled in the study of the relationships between occupational stress and health self-reports.</p>

Relationship between social support and occupational stress / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To explore the relationship between social support and occupational stress.</p><p><b>METHODS</b>A cross-sectional survey involving 654 career people from different industries was conducted. Social support, the occupational stressors, personalities, and occupational strain were measured by using Occupational Stress Instrument.</p><p><b>RESULTS</b>The people from different occupations got different level of social support. Social support scores were significantly positively related to interpersonal relation, responsibility for people, responsibility for thing, advancement and participation, task identity, training adequacy, challenge, autonomy, job satisfaction, mental health, affective ambulance, positive emotion, self-esteem and coping strategy (P<0.05 or P<0.01), negatively to careers, role conflict, role ambiguity, job future ambiguity, negative emotion, depression symptoms, daily life stress and work locus of control scores (P<0.05 or P<0.01). The scores of interpersonal relation, responsibility for people, responsibility for thing, advancement and participation, task identity, training adequacy, challenge, autonomy, job satisfaction, mental health, affective ambulance, positive emotion, self-esteem and coping strategy with sufficient social support were significantly higher than those of deficient social support (P<0.05 or P<0.01). The scores of role conflict, role ambiguity, job future ambiguity, negative emotion, depression symptoms, daily life stress and work locus of control were higher than those of the latter (P<0.05 or P<0.01). Stepwise regression analysis showed that social support was the predictor of depression (R(2)>0.05).</p><p><b>CONCLUSION</b>Social support affects occupational stress largely and plays an important role in maintaining mental health of career people. The people from different occupations get different level of social support.</p>